Interferon-beta-1b-induced short- and long-term signatures of treatment activity in multiple sclerosis

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Application of Interferon Beta-1b in Multiple Sclerosis

Recombinant interferon beta-1b (IFNβ-1b) was the first approved disease-modifying therapy for patients with multiple sclerosis (MS) by the world regulatory agencies for medical drugs and devices. IFNβ-1b significantly decreases the inflammatory component of MS but still has doubtable effect on the neurodegenerative component. This article appraises the beneficial effects of IFNβ-1b on clinical ...

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Acute acneiform eruption induced by interferon beta-1b during treatment for multiple sclerosis.

Multiple sclerosis is an inflammatory demyelinating disease of presumed autoimmune origin that affects the central nervous system. The main form of therapy is based on the use of immunomodulators such as interferon beta, which are usually well tolerated. Skin manifestations resulting from treatment with interferon beta-1b consist principally of reactions at the site of subcutaneous application ...

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Review of interferon beta-1b in the treatment of early and relapsing multiple sclerosis

Multiple sclerosis (MS) is the most common autoimmune illness of the central nervous system. For many years the inflammatory manifestations of MS were treated using only corticosteroids. Since the 1990s the results of several clinical trials with immunomodulatory agents have changed the therapeutic approach to this disease. Interferon beta (IFNbeta)-1b represents the pioneer of those therapies....

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interferon-beta in pediatric multiple sclerosis patients: safety in short-term prescription

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ژورنال

عنوان ژورنال: The Pharmacogenomics Journal

سال: 2012

ISSN: 1470-269X,1473-1150

DOI: 10.1038/tpj.2012.27